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. 2020 Jun 8;9:e57028. doi: 10.7554/eLife.57028

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© 2020, Gawrys-Kopczynska et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 4. — Box plot comparing the expression proﬁles of ATG (angiotensinogen), AT1A (angiotensin II receptor type 1a), AT1B (angiotensin II receptor type 1b), AT2 (angiotensin II receptor type 2), TGF-b (transforming growth factor-beta), TIMP2 (metalloproteinase inhibitor 2) in hearts of SD – Sprague-Dawley rats, SHHF - Spontaneously Hypertensive Heart Failure (SHHF/MccGmiCrl-Lepr^cp/Crl), SD-ISO - SD rats treated with ISO at the age of 56 week, drinking either water (control groups) or TMAO solution, (n = 6–7 for each series). × - mean value, * indicates significant difference compared with the control group. *p<0.05 by t-test or Mann-Whitney U test.

Figure 4—source data 1. Real-time RT-PCR analysis, expression profiles in heart.

elife-57028-fig4-data1.xlsx^{(105.8KB, xlsx)}