Table 3.

Parameter estimates of $R_2^{’},$ DBV, and OEF using three qBOLD models: linear model (L) considering only tissue signal at long-τ and τ = 0 data-points; a one-compartment model (1C) considering tissue signal across all τ; and a two-compartment model (2C) that includes intravascular signal. Both 1C and 2C models include spatial regularization. The table shows grey matter mean ± grey matter inter-voxel standard deviation, for 7 healthy subjects, and group mean ± group standard deviation.

Model	${\mathit{\text{R}}}_2^{’}\left({\text{s}}^{-1}\right)$					DBV (%)					OEF (%)
	L	1C	1C	2C	2C	L	1C	1C	2C	2C	L	1C	1C	2C	2C
Regularization	None	None	Spatial	None	Spatial	None	None	Spatial	None	Spatial	None	None	Spatial	None	Spatial
1	3.1±1.9	3.6±1.1	3.6±1.0	3.6±1.3	3.6±1.0	4.9±3.9	6.7±3.2	6.7±3.6	6.4±3.0	6.4±3.5	24±17	19±11	22±12	20±11	23±13
2	3.7±2.8	3.9±1.4	4.2±1.4	4.0±1.8	4.2±1.4	6.3±5.4	7.4±4.0	7.6±4.4	7.1±3.8	7.1±4.2	20±14	17±11	18±11	17±11	20±12
3	3.0±2.7	3.2±1.1	3.4±1.2	3.5±1.7	3.5±1.2	4.4±3.9	6.6±3.1	6.6±3.4	6.4±2.9	6.4±3.2	23±17	16±11	19±12	17±11	19±12
4	3.5±3.2	3.9±1.3	4.3±1.3	4.1±1.8	4.4±1.4	5.4±5.1	7.3±3.4	7.5±3.8	6.7±3.1	7.4±3.7	21±14	17±10	17±10	19±11	18±11
5	3.1±2.9	3.4±1.4	3.4±1.5	3.9±2.1	3.3±1.8	5.8±5.4	6.9±3.4	6.9±3.6	6.1±3.0	6.8±3.6	20±14	16±11	18±12	18±12	20±14
6	3.5±2.9	3.9±1.1	4.1±1.2	4.0±1.4	4.2±1.2	5.8±5.8	6.6±3.3	6.5±3.6	6.0±2.9	6.5±3.6	23±17	19±12	20±12	21±12	22±12
7	2.8±2.6	2.9±1.4	3.0±1.8	3.5±2.7	2.8±2.0	5.2±5.1	6.1±3.5	6.2±3.7	5.8±3.1	6.6±3.7	18±15	16±13	16±13	16±15	18±15
Mean	3.2±0.3	3.5±0.4	3.8±0.4	3.8±0.4	3.6±0.4	5.4±0.6	6.8±0.4	6.9±0.5	6.4±0.4	6.7±0.4	21±2	17±2	19±2	18±2	20±2