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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2020 May 8;29(7):1381–1388. doi: 10.1158/1055-9965.EPI-19-1560

Table 1.

Participant characteristics (N=2,358). Unadjusted mean (SD) or N (%).

Characteristic No Cancer (n=691) Cancer (n=1,667) Gleason 8+ PCa (n=370) Aggressive PCa (n=543) Death due to PCa (n=93) Non-Aggressive PCa (n=1,011)
Demographic/Clinical Characteristics
Age at Diagnosis -- 73.0 (7.6) 75.5 (8.0) 74.1 (8.2) 75.1 (7.9) 72.2 (7.2)
Birth Year 1931 (7.0) 1933 (7.8) 1931 (7.4) 1933 (7.8) 1929 (7.1) 1934 (7.7)
Blood Draw Year 2002 (2.3) 2002 (2.4) 2002 (2.3) 2002 (2.3) 2001 (2.4) 2002 (2.4)
Age at Blood Draw 71.6 (6.6) 68.9 (7.5) 71.1 (7.3) 69.9 (7.6) 71.9 (6.9) 68.3 (7.5)
BMI at Blood Draw 26.4 (4.2) 26.5 (4.0) 26.5 (3.9) 26.7 (4.0) 26.6 (4.0) 26.5 (4.0)
Area
Hawaii 331 (48) 836 (50) 220 (59) 296 (55) 27 (29) 510 (50)
Los Angeles 360 (52) 831 (50) 150 (41) 247 (45) 66 (71) 501 (50)
Ethnicity
Japanese 218 (32) 539 (32) 144 (39) 184 (34) 11 (12) 333 (33)
African American 156 (23) 363 (22) 64 (17) 108 (20) 37 (40) 216 (21)
Latino 153 (22) 347 (21) 53 (14) 97 (18) 24 (26) 214 (21)
White 131 (19) 325 (19) 84 (23) 118 (22) 20 (22) 192 (19)
Native Hawaiian 33 (5) 93 (6) 25 (7) 36 (7) 1 (1) 56 (6)
Tumor Characteristics
Gleason Score
7 -- 1,231 (74) 0 145 (27) 35 (38) 1,011 (100)
8 -- 370 (22) 370 (100) 370 (68) 42 (45) 0
NA 691 (100) 66 (4) 0 28 (5) 16 (17) 0
Stage
Localized -- 1,308 (78) 252 (68) 279 (51) 39 (42) 1,011 (100)
Regional -- 153 (9) 49 (13) 153 (28) 8 (9) 0
Metastatic -- 79 (5) 43 (12) 79 (15) 38 (41) 0
NA 691 (100) 127 (8) 26 (7) 32 (6) 8 (9) 0
4K Markers
Total PSA (ng/mL) 4.60 (4.94) 7.58 (16.15) 10.23 (23.74) 10.32 (22.73) 21.49 (38.16) 5.62 (5.56)
Free PSA (ng/mL) 1.13 (0.88) 1.31 (3.16) 1.74 (6.05) 1.72 (5.30) 3.65 (9.04) 1.07 (0.84)
Intact PSA (ng/mL) 0.55 (0.43) 0.74 (2.21) 1.06 (4.25) 1.05 (3.75) 2.47 (6.66) 0.57 (0.50)
hK2 (ng/mL) 0.09 (0.14) 0.11 (0.18) 0.15 (0.29) 0.15 (0.28) 0.29 (0.43) 0.10 (0.10)
4K Score (%) 15.3 (15.5) 27.5 (24.2) 35.7 (26.9) 34.7 (27.3) 50.1 (32.5) 24.7 (21.1)