Table 1.
Characteristic | No Cancer (n=691) | Cancer (n=1,667) | Gleason 8+ PCa (n=370) | Aggressive PCa (n=543) | Death due to PCa (n=93) | Non-Aggressive PCa (n=1,011) |
---|---|---|---|---|---|---|
Demographic/Clinical Characteristics | ||||||
Age at Diagnosis | -- | 73.0 (7.6) | 75.5 (8.0) | 74.1 (8.2) | 75.1 (7.9) | 72.2 (7.2) |
Birth Year | 1931 (7.0) | 1933 (7.8) | 1931 (7.4) | 1933 (7.8) | 1929 (7.1) | 1934 (7.7) |
Blood Draw Year | 2002 (2.3) | 2002 (2.4) | 2002 (2.3) | 2002 (2.3) | 2001 (2.4) | 2002 (2.4) |
Age at Blood Draw | 71.6 (6.6) | 68.9 (7.5) | 71.1 (7.3) | 69.9 (7.6) | 71.9 (6.9) | 68.3 (7.5) |
BMI at Blood Draw | 26.4 (4.2) | 26.5 (4.0) | 26.5 (3.9) | 26.7 (4.0) | 26.6 (4.0) | 26.5 (4.0) |
Area | ||||||
Hawaii | 331 (48) | 836 (50) | 220 (59) | 296 (55) | 27 (29) | 510 (50) |
Los Angeles | 360 (52) | 831 (50) | 150 (41) | 247 (45) | 66 (71) | 501 (50) |
Ethnicity | ||||||
Japanese | 218 (32) | 539 (32) | 144 (39) | 184 (34) | 11 (12) | 333 (33) |
African American | 156 (23) | 363 (22) | 64 (17) | 108 (20) | 37 (40) | 216 (21) |
Latino | 153 (22) | 347 (21) | 53 (14) | 97 (18) | 24 (26) | 214 (21) |
White | 131 (19) | 325 (19) | 84 (23) | 118 (22) | 20 (22) | 192 (19) |
Native Hawaiian | 33 (5) | 93 (6) | 25 (7) | 36 (7) | 1 (1) | 56 (6) |
Tumor Characteristics | ||||||
Gleason Score | ||||||
≤7 | -- | 1,231 (74) | 0 | 145 (27) | 35 (38) | 1,011 (100) |
≥8 | -- | 370 (22) | 370 (100) | 370 (68) | 42 (45) | 0 |
NA | 691 (100) | 66 (4) | 0 | 28 (5) | 16 (17) | 0 |
Stage | ||||||
Localized | -- | 1,308 (78) | 252 (68) | 279 (51) | 39 (42) | 1,011 (100) |
Regional | -- | 153 (9) | 49 (13) | 153 (28) | 8 (9) | 0 |
Metastatic | -- | 79 (5) | 43 (12) | 79 (15) | 38 (41) | 0 |
NA | 691 (100) | 127 (8) | 26 (7) | 32 (6) | 8 (9) | 0 |
4K Markers | ||||||
Total PSA (ng/mL) | 4.60 (4.94) | 7.58 (16.15) | 10.23 (23.74) | 10.32 (22.73) | 21.49 (38.16) | 5.62 (5.56) |
Free PSA (ng/mL) | 1.13 (0.88) | 1.31 (3.16) | 1.74 (6.05) | 1.72 (5.30) | 3.65 (9.04) | 1.07 (0.84) |
Intact PSA (ng/mL) | 0.55 (0.43) | 0.74 (2.21) | 1.06 (4.25) | 1.05 (3.75) | 2.47 (6.66) | 0.57 (0.50) |
hK2 (ng/mL) | 0.09 (0.14) | 0.11 (0.18) | 0.15 (0.29) | 0.15 (0.28) | 0.29 (0.43) | 0.10 (0.10) |
4K Score (%) | 15.3 (15.5) | 27.5 (24.2) | 35.7 (26.9) | 34.7 (27.3) | 50.1 (32.5) | 24.7 (21.1) |