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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Clin Cancer Res. 2020 Apr 2;26(13):3384–3396. doi: 10.1158/1078-0432.CCR-19-3487

Figure 3. Analysis of activation, maturation, checkpoint, proliferation and senescence markers on MART-1 Tet+ CD8+ T-cells expanded by DCs or nano-aAPC.

Figure 3.

(A-E) Expression of activation (A, CD69, 4–1BB, ICOS and OX-40), maturity (B, CD27 and CD28), checkpoint (C, PD-1, Tim3 and LAG3), proliferation (D, Ki67) and senescence molecules (E, KLRG1) on MART-1 Tet+ CD8+ T-cells expanded by DCs or nano-aAPC from the same melanoma patients (n=6). Significance was assessed by Student’s two-tailed paired t test.