Table 2.

Clinical characteristics of the bacteremic patients and hospitalized controls

	Bacteremic population			Control population
	No. (%) of patients
	GNB (n = 20)	SAB (n = 20)	P value (GNB, SAB)	Hospitalized, noninfected controls (n = 10)	P value (GNB, SAB, controls)
Comorbidity
BMI, median (IQR)	28.3 (24.9–34.0)	30.1 (24.4–35.3)	0.6263	36.1 (24.1–37.7)	0.6256
Diabetes	2 (10)	7 (35)	0.127	5 (50)	0.04333
Hemodialysis-dependent prior to Infection	0 (0)	3 (15)	0.231	0 (0)	0.21429
Neoplasm	11 (55)	3 (15)	0.019	1 (10)	0.00791
Rheumatoid arthritis	0 (0)	1 (5)	1.000	1 (10)	0.67347
Immunosuppressive therapy	8 (40)	8 (40)	1.000	2 (20)	0.865
Transplant recipient	2 (10)	2 (10)	1.000	0 (0)	0.67000
HIV+	1 (5)	1 (5)	1.000	0 (0)	1.00000
Median APACHE II Score (IQR)	15.0 (11.5–17.0)	15.5 (10–19.5)	0.735	13.5 (6.0–24.0)	0.5881
Disease manifestations
Fever	14 (70)	14 (70)	1.000	0 (0)	0.00021
Malaise	7 (35)	13 (65)	0.113	1 (10)	0.01097
Edema	4 (20)	8 (40)	0.301	1 (10)	0.19657
WBC (IQR)	13.9 (7.7–19.2)	11.3 (7.1–20.0)	0.695	6.0 (3.5–8.1)	0.0452
Lactate (IQR)	2.0 (0.8–4.4)	1.6 (0.8–1.8)	0.169	1.7 (1.2–1.9)	0.2948
Creatinine (IQR)	1.05 (0.8–2.0)	2.2 (1.4–3.5)	0.010	1.25 (0.9–2.7)	0.0285
Source of Infection (%)			0.022
Endovascular	4 (20)	9 (45)
Skin/soft tissue	3 (15)	8 (40)
GU/GI	8 (40)	2 (10)
Other	2 (10)	0 (0)
Unknown primary	3 (15)	1 (5)
Outcomes
Death (all cause) 30 days	4 (20)	2 (10)	0.661
Septic shock	2 (10)	1 (5)	1.000
Acute respiratory distress syndrome	0 (0)	1 (5)	1.000
Acute renal failure	7 (35)	4 (20)	0.480
Persistent bacteremia	1 (5)	9 (45)	0.008

GNB Gram-negative bacteremia, SAB S. aureus bacteremia, IQR interquartile range, BMI body mass index, HIV+ human immunodeficiency virus positive, WBC white blood cell, GU genitourinary, GI gastrointestinal