Table 5.

Residue types at the hypervariable positions for WT Nb474 and mutant Nb474 optimized for TcoALD

	28	31	32	53	103	104	105	106	108	110	115	125	126
WT	ALA	TYR	TYR	ARG	ASP	THR	THR	ASP	TYR	SER	TYR	ASP	TYR
Mutant	ARG	GLU	ALA	HIS	ASN	ASP	LEU	GLN	LEU	LYS	TYR	ASP	GLN