Table 6.
Residue types at the hypervariable positions for WT cAbHuL5 and mutant cAbHuL5 optimized for HuL
27 | 28 | 29 | 30 | 31 | 55 | 56 | 97 | 98 | 101 | 110 | 111 | 112 | 113 | 115 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
WT | LEU | SER | THR | THR | VAL | PHE | PRO | LYS | THR | PHE | SER | ARG | ALA | TYR | HIS |
Mutant | LEU | ASN | ASP | GLU | GLN | ASP | GLN | ALA | LEU | LEU | TRP | SER | LYS | TRP | VAL |