Table 1.

Modified score of quality from CAMARADES for systemic reviews in experimental animal studies [24]: [1] peer-reviewed journal; [2] control group; [3] randomisation; [4]VEGF dose justified; [5] blinding; [6] details on animal model; [7] sample size calculation; [8] compliant with ethics; and [9] no conflicts of interest.

References	1) Peer review journal	2) Control group	3) Randomi -zation	4) VEGF dose justified	5) Blinding	6) Details on animal model	7) Sample size calculation	8) Comply with ethics	9) No conflict of interest	Quality Score
Amirian 2015 [23]	X	X	—	—	—	X	—	X	—	4
Kenney 2009 [32]	X	X	—	—	—	—	—	X	—	3
Lohse 2015 [24]	X	X	—	X	—	—	—	—	—	3
Çakir-Özkan 2017 [34]	X	X	—	—	—	X	—	X	—	4
L Zhang 2014 [42]	X	X	—	—	X	X	—	X	X	6
Lv 2015 [35]	X	X	X	—	—	—	—	X	—	4
Khojasteh 2017 [43]	X	X	—	—	X	—	—	X	—	4
Moser 2017 [25]	X	X	X	X	X	—	—	X	X	7
W Zhang 2014 [36]	X	X	—	—	—	—	—	X	—	3
W Zhang 2011 [37]	X	X	X	—	—	—	—	X	—	4
Quinlan 2015 [26]	X	X	—	X	X	X	—	X	X	7
Schliephake 2015 [27]	X	X	—	—	X	X	X	X	X	7
Behr 2012 [33]	X	X	—	X	—	X	—	X	X	6
Geuze 2012 [44]	X	X	X	X	—	X	X	X	X	8
Hernández 2012 [38]	X	X	—	—	—	X	—	X	—	4
Kempen 2009 [28]	X	X	—	X	—	X	—	X	—	4
Casap 2008 [39]	X	X	X	—	X	X	—	X	—	6
Patel 2008 [29]	X	X	—	X	X	X	—	X	—	6
Yang 2010 [40]	X	X	—	—	X	X	—	X	—	5
Yonamine 2010 [30]	X	X	—	—	—	—	—	X	—	3
Wu 2012 [41]	X	X	X	—	X	X	—	X	X	7
Schmitt 2013 [46]	X	X	—	X	—	X	—	X	—	5
Du 2015 [45]	X	X	X	—	X	X	—	X	X	7
Das 2016 [31]	X	X	—	X	—	X	X	X	—	5