Table 2.

Regions showing significant functional resting-state connectivity with the striatal seeds depicted in Fig. 1A

Seed	Effect	Significant cluster	No. of voxels	Peak MNI coordinates	Brodmann areas
Ventromedial caudate	Familial Risk	OFC, mPFC, rostral ACC,	143	−9, 39, −9	11
		mPFC	21	9, 36, −15	11
		mPFC	19	−6, 66, 6	10
	Stimulant Use	PCC	10	−3, −24, 42	23, 31
	Interaction	IFG, middle frontal gyrus	78	42, 36, 6	45, 46
Ventrolateral putamen	Stimulant Use	Insula	126	−39, 6, −3	48
		Supramarginal gyrus	79	57, −30, 42	40
		Supramarginal gyrus	57	−57, −42, 36	39, 40
	Interaction	ACC	2	9, 30, 18	32, 24
Dorsolateral putamen (posterior)	Interaction	Central opercular cortex	35	57, 3, 9	48, 6
		Superior medial frontal cortex, SMA, cingulate gyrus (middle), insula	10	0, 12, 45	6, 32
			6	15, 9, 39	32, 24
			3	39, 6, 6	13

ACC, anterior cingulate cortex; IFG, inferior frontal gyrus; mPFC, medial prefrontal cortex; OFC, medial and lateral parts of the orbitofrontal cortex; PCC, posterior cingulate cortex; SMA, supplementary motor area.