Fig. 4.

Changes over 3 months in node eigenvector and node betweenness centrality between patients and controls. The AAL regions that showed significant differences in node centrality between patients and controls over 3 months are represented by a node/circle and overlaid within a brain volume. Nodes coloured in blue show the AAL regions where patients had an increase in node eigenvector/betweenness centrality in comparison to controls over 3 months. Nodes coloured in red show the AAL regions in which patients had a significant reduction in eigenvector or betweenness centrality in comparison to controls. Scatter plots show the observed and predicted (null model) change in patients after surgery for those AAL regions. Positive values suggest an increase of eigenvector or betweenness centrality following surgery. The scatter plots therefore compare the impact on centrality measures of the surgical resection alone with the overall changes seen post-operatively. A table with the names and abbreviations of all regions can be found in Table S8. AC – Anterior cingulum; AMY – Amygdala; ANG – Angular; CAL – Calcarine; CAU – Caudate; HIP – Hippocampus; INS – Insula; IO – Inferior occipital; IP – Inferior parietal; LIN – Lingual; MC - Middle cingulum; OLF – Olfactory; ORBinf - Inferior frontal, orbital; ORBmid - Middle frontal, orbital; ORBsup - Superior frontal, orbital; ORBsupmed - Superior frontal, medial; PAL – Pallidum; PC - Posterior cingulum; PCL – Paracentral lobule; PHIP – Parahippocampal; PoC – Postcentral; PUT – Putamen; REC – Rectus; ROL - Rolandic operculum; SP – Superior parietal; THAL – Thalamus; TPOsup – Superior Temporal Pole. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)