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. 2020 Jun 24;2020:3903125. doi: 10.1155/2020/3903125

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Copyright © 2020 Linyu Lu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Crocin recovered CUMS-induced depression-related behavior. (a) The sucrose preference test. ANOVA, F (3, 26) = 38.07, P < 0.0001. (b, c) The immobility time in TST and FST. ANOVA, F (3, 26) = 56.74, P < 0.0001; ANOVA, F (3, 26) = 16.72, P < 0.0001. (d, e) The food consumption and feeding latency in NSF. ANOVA, F (3, 25) = 37.15, P < 0.0001; ANOVA, F (3, 26) = 33.55, P < 0.0001. (f, g) The total distance and time in center in OFT. ANOVA, F (3, 22) = 1.019, P = 0.4031; ANOVA, F (3, 26) = 1.238, P = 0.3162. All data are expressed as mean ± SEM. ∗P < 0.05, ^∗∗P < 0.01 versus saline; ^#P < 0.05, ^##P < 0.01 versus CUMS.