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. 2020 Jun 25;2020:2375676. doi: 10.1155/2020/2375676

Figure 2.

Figure 2

Composition of gut microbiota changed quickly in db/db mice. Glucose level and body weight rose quickly in 4- to 8-week-old db/db mice. (a) Food intake, (b) glucose level, (c) body weight, and (d) body weight gain were measured in 4- to 8-week-old mice. (e) Plots were generated using the weighted version of UniFrac-based PCoA with the PERMANOVA significance test. (f) Heatmap showed the relative abundance of prepended higher taxon genuses (19 enriched and 9 decreased ones in db/db mice). (g) The analysis of differences in the microbial taxa between db/db mice and WT animals using LEfSe (linear discriminant analysis (LDA) coupled with effect size measurements). Only bacterial taxa reaching a LDA threshold of 2 with a p value < 0.05 are shown.