Table 2.

Frequency of detectable plasma EGFR mutations at P0 in each patient characteristics.

P0 activating mutation	+	–	Total	Frequency(%)
Total	147	68	215	68.4
Age
75<	123	52	175	70.3
>=75	24	16	40	60.0
Sex
Male	57	21	78	73.1
Female	90	47	137	65.7
Smoking status
Non smoker	84	39	123	68.3
Former light smoker	7	6	13	53.8
Other smoker	56	23	79	70.9
PS
0	75	52	127	59.1
1	70	16	86	81.4
2	2	0	2	100.0
Histology
adeno	145	68	213	68.1
large	1	0	1	100.0
other	1	0	1	100.0
EGFR subtype
Exon 19 del	76	30	106	71.7
Exon 21 L858R	71	38	109	65.1
Stage
IIIB	12	2	14	85.7
IV (M1a)	26	23	49	53.1
IV (M1b)	93	18	111	83.8
Recurrence	16	25	41	39.0
Metastatic sites (Stage IV)
PUL only	6	8	14	42.9
PLE only	17	15	32	53.1
BRA only	9	4	13	69.2
Others	87	14	101	86.1