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Transcription by the influenza virus RNA polymerase. (A) Association of the influenza virus RNA polymerase with the serine-5 phosphorylated carboxy-terminal domain (CTD) of host RNA polymerase II (Pol II) and cap-snatching. (B) Schematic model of the influenza virus RNA polymerase showing the binding of capped RNA primer and template before transcription initiation (top) and elongation and duplex unwinding during transcription (bottom). (PL) Priming loop.
