Figure S2.

Activation by kainate or glutamate plus cyclothiazide. Summary plot of current (mean ± SEM, 5–14 cells per construct) evoked by 100 µM kainate or by 1 mM glutamate plus 30 µM cyclothiazide in HEK293 cells transfected with WT, A8C, or L10C mutant GluA1, alone or cotransfected with γ-2 TARP. *, both A8C and L10C mutants were significantly different from WT; †, A8C was significantly different from L10C; #, L10C with γ-2 TARP was significantly different from L10C alone two-way ANOVA with post hoc Student–Newman-Keuls test).