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. 2020 Jul 3;10:11003. doi: 10.1038/s41598-020-67411-w

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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T1-weighted MRI images (top) showing contrast-enhancing lesions for all three groups (a) GL261, (b) GL261-Luc2, and (c) GL261 Red-FLuc implanted tumors at respective tumor dose. T2-weighted MRI (bottom) of (d) GL261, (e) GL261-Luc2, and (f) GL261 Red-FLuc tumors with tumor volumes correlating with onset of neurological deficits and symptoms All images in this figure were created using Microsoft PowerPoint Office 365 https://www.microsoft.com/enus/p/powerpoint/cfq7ttc0k7c6?activetab=pivot:overviewtab and Osirix DICOM Viewer https://www.osirix-viewer.com/.