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. 2020 Jul 3;11:3364. doi: 10.1038/s41467-020-16734-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Top: when the tract was calculated exclusively based on data from the ALIC cohort, it was used to calculate fiber T-scores for all patients in the STN cohort. These were correlated with clinical improvements in the STN cohort. One example patient with strong overlap of the tract (yellow) received a high fiber T-score, whereas one with less overlap received a lower score (blue). The two example patients are marked in the correlation plot on the left. Bottom: here, the tract was calculated exclusively on data from the STN cohort to predict outcome in patients in the ALIC cohort. Again, two example patients are shown. Gray shaded areas in the correlation plots represent 95% confidence intervals. Of note, here, some VTAs barely overlapped with the tract (as the blue example VTA) and consequently received a near-zero score.