Table 1.
Patient demographic details and clinical results of the two cohorts.
| ALIC-DBS cohort (mean ± SD) |
STN-DBS cohort (mean ± SD) |
NAcc DBS cohort (mean ± SD) |
Combined DBS cohort (mean ± SD) |
|
|---|---|---|---|---|
| Center | University Hospital Cologne | University Hospital Grenoble | Hospital Clínico San Carlos Madrid | University Hospital London |
| Reference(s) | [22, 31] | [28] | [40] | [16] |
| N of patients (females) | 22 (12) | 14 (9) | 8 (4) | 6 (1) |
| N of electrodes | 44 | 28 | 16 | 24 |
| Age | 41.7 ± 20.5 | 41 ± 9 | 35.3 ± 10.4 | 45.5 ± 10.5 |
| Y-BOCS baseline | 31.3 ± 4.4 | 33.4 ± 3.7 | 30 ± 7.75 | 36.2 ± 1.8 |
| Y-BOCS after DBS | 20.7 ± 7.7 (12 months postop) | 19.6 ± 10.6 (12 months postop) | 14.75 ± 7.2 (3 months postop of best contact) | 14.3 ± 4.1 (optimized phase in ref. 16) |
| Absolute Y-BOCS Improvement | 9.6 ± 6.5 | 13.8 ± 10.8 | 15.1 ± 9.6 | 21.83 ± 5.7 |
| % Y-BOCS Improvement | 31.0 ± 20.5% | 41.2 ± 31.7% | 47.8 ± 23 | 50.0 ± 12.6% |