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. 2020 Jul 3;11:3364. doi: 10.1038/s41467-020-16734-3

Table 2.

DBS targets for treatment of OCD defined in the literature.

DBS target References Number of patients % Y-BOCS change AC/PC coordinates Relative to Target type MNI coordinates (Fig. 5)
STN Mallet et al.66 8 32.1 NA AC Tip of the electrode ±11.30 −9.90 −7.81
amGPi Nair et al.9 4a NA ±14.47 9.85 −3.28 MCP Tip of the electrode ±15.66 −1.41 −8.22
VC/VS Tsai et al.67 1 7.7 ±7.5 16.3 −3.05 MCP Tip of the electrode ±7.92 5.51 −9.01
slMFB Coenen et al.10 2 41.7 (at 12 months) ±7.6 −1.72 −3.0 MCP Active contacts ±8.35 −13.64 −7.00
NAcc Sturm et al.5 4 NA ±6.5 2.5 −4.5 AC Tip of the electrode ±6.98 3.69 −10.55
ALIC Nuttin et al.68 6 38.7 ±13 3.5 0 AC Tip of the electrode ±13.84 5.17 −5.04
MD Maarouf et al.11 4 10.7 ±4.7 −18.52 4.87 AC Active contacts ±5.10 −18.17 2.59
VA Maarouf et al.11 4 10.7 ±6.84 −13.76 7.78 AC Active contacts ±7.52 −12.68 5.60
iml Maarouf et al.11 4 10.7 ±5.78 −14.9 7.08 AC Active contacts ±6.36 −13.99 4.85
ITP Lee et al.69 5 52.0 ±6.5 −3 −0.5 AC Tip of the electrode ±6.92 −1.84 −5.13
BNST Nuttin et al.70 4 NA ±6 0 0 AC Tip of the electrode ±6.33 1.39 −4.87

MD medial dorsal thalamic nucleus, VA ventral anterior thalamic nucleus, iml internal medullary lamina, MCP mid-commissural point, AC anterior commissure.

aTourette patients, with prominent symptoms of OCD.