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. 2020 Jul 3;11:3354. doi: 10.1038/s41467-020-17129-0

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© The Author(s) 2020, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a UPF1 and G3BP1 localization in HeLa cells expressing either GFP only, repeat RNA, or GFP-tagged DPR. Stress granules are indicated by arrowheads. Scale bar, 10 µm. Similar results were obtained from four independent experiments. b Quantification of stress granule (SG)-positive cells. n = 4 independent experiments. Data are presented as mean values ± SD. ***P < 0.001, two-sided unpaired t tests. c Quantification of stress granule formation in G3BP-WT and -DKO cells. n = 3 independent experiments. Data are presented as mean values ± SD. **P < 0.01, two-sided unpaired t tests. d Changes in UPF1 target mRNA abundance in G3BP-WT and -DKO cells. Expression levels were normalized to the GFP-only control. n = 3 independent experiments. Data are presented as mean values ± SD. *P < 0.05; **P < 0.01, two-sided ratio t tests. Source data and exact P values are provided in the Source Data file.