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. 2020 Jul 3;11:3354. doi: 10.1038/s41467-020-17129-0

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© The Author(s) 2020, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Representative images of mApple-labeled primary cortical neurons expressing BFP (vector), UPF1, or NMD-deficient UPF1 mutants before and after treatment of 2 µM PR₂₀ for 48 h. Scale bar, 100 µm. b Quantification of neuronal survival after 48 h of PR₂₀ treatment. Numbers of independent experiments are indicated in parenthesis. Data are presented as mean values ± SD. **P < 0.01; n.s., not significant, two-sided paired t tests. Source data and exact P values are provided in the Source Data file.