Table 6.
Modularity structure in IBS patients and healthy controls.
| Sendai cohort | |||
| HC | |||
| L/R amygdala | L/R hippocampus | L/R middle insula | |
| L/R angular gyrus | L/R pACC | L/R thalamus | |
| L/R anterior insula | L/R vlPFC | L/R precuneus | |
| L LTC | PAG | L IPL | |
| L/R PCC | L posterior insula | L parahippocampal gyrus | |
| L/R putamen | L pMCC | R posterior insula | |
| L SI | R IPL | R SI | |
| L SII | R LTC | R pMCC | |
| L/R aMCC | R SII | ||
| L/R dlPFC | |||
| L/R mPFC | |||
| R parahippocampal gyrus | |||
| L/R sACC | |||
| IBS | |||
| L/R amygdala | L/R angular gyrus | L/R PCC | L/R posterior insula |
| L/R hippocampus | L/R IPL | L/R aMCC | L/R putamen |
| L/R anterior insula | L/R thalamus | L/R dlPFC | L/R SII |
| L/R middle insula | L/R pACC | L/R precuneus | L/R mPFC |
| L/R vlPFC | L LTC | L sACC | R pMCC |
| L parahippocampal gyrus | L pMCC | R parahippocampal gyrus | |
| L/R SI | R sACC | ||
| PAG | |||
| R LTC | |||
| Gothenburg cohort | |||
| HC | |||
| L/R angular gyrus | L/R hippocampus | L/R middle insula | |
| L/R LTC | L/R IPL | L/R posterior insula | |
| L/R mPFC | L/R thalamus | L/R PCC | |
| L/R precuneus | L/R SI | L/R putamen | |
| L amygdala | L/R pACC | L/R SII | |
| L sACC | L anterior insula | L/R aMCC | |
| R dlPFC | L dlPFC | L/R parahippocampal gyrus | |
| R pMCC | L/R vlPFC | ||
| L pMCC | |||
| PAG | |||
| R amygdala | |||
| R anterior insula | |||
| R sACC | |||
| IBS | |||
| L/R amygdala | L/R angular gyrus | L/R posterior insula | |
| L/R hippocampus | L/R LTC | L/R PCC | |
| L/R anterior insula | L/R SI | L/R aMCC | |
| L/R IPL | L/R SII | L/R dlPFC | |
| L/R putamen | L/R parahippocampal gyrus | L/R mPFC | |
| L/R thalamus | L/R vlPFC | L/R pACC | |
| L middle insula | L/R pMCC | ||
| PAG | L/R precuneus | ||
| L/R sACC | |||
| R middle insula |
IBS, irritable bowel syndrome; L, left; R, right; IPL, inferior parietal lobule; LTC, lateral temporal cortex; PCC, posterior cingulate cortex; SI/SII, primary/secondary somatosensory cortex; aMCC, anterior midcingulate cortex; dlPFC, dorsolateral prefrontal cortex; mPFC, medial prefrontal cortex; pACC, pregenual anterior cingulate cortex; pMCC, posterior midcingulate cortex; sACC, subgenual anterior cingulate cortex; vlPFC, ventrolateral prefrontal cortex; PAG, periaqueductal grey matter.