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. 2020 Jun 30;13:2037–2052. doi: 10.2147/IDR.S255292

Table 3.

Sensitivities, Specificities, Positive Predictive and Negative Predictive Values for Phenotypic and HRMA (blaSHV Gene for ESBL-Producing, blaKPC Gene for Carbapenemase-Producing and blaVIM Gene for MBL-Producing) Methods in β-Lactamase-Producing Strain of P. aeruginosa

Methods No. of P. aeruginosa Strains (Total n = 88)
KPC Strains (Total n = 12) MBL Strains (Total n = 5) ESBL Strains (Total n = 39) Sen (%) Sp (%) PPV (%) NPV (%)
True Positive False Positive False Negative True Negative True Positive False Positive False Negative True Negative True Positive False Positive False Negative True Negative
DDT 0 0 0 0 0 0 0 0 43 4 2 86 95.55 95.55 91.48 97.72
EIM assay 0 0 0 0 7 2 2 81 0 0 0 0 77.77 97.59 97.59 77.77
Hodge test 11 1 1 76 0 0 0 0 0 0 0 0 91.66 98.70 91.66 98.70
Carba-NP 19 4 2 74 0 0 0 0 0 0 0 0 90.47 94.87 97.36 82.60
HRM 12 0 0 76 5 0 0 83 39 0 0 69 100 100 100 100
Gold Standard 12 0 0 76 5 0 0 83 39 0 0 69 100 100 100 100

Abbreviations: Sen, sensitivity; Sp, speciation; PPV, positive predictive values; NPV, negative predictive values.