Table 5.
Relationship of Antibiotic Susceptibility Profiles, β-Lactamase Class and Sensitivity/Specificity of Phenotypic and HRMA in Clinical Isolates of P. aeruginosa
Antibiotics Resistance | Methods | |||||
---|---|---|---|---|---|---|
DDT | EIM | Hodge test | Carba-NP | HRMA | Gold Standard | |
Ceftazidime | 0.071 | 0.040 | 0.832 | 0.097 | 0.033 | 0.077 |
Doripenem | 0.097 | 0.020 | 0.065 | 0.009 | 0.832 | 0.089 |
Meropenem | 0.193 | 0.080 | 0.073 | 0.043 | 0.193 | 0.193 |
Imipenem | 0.169 | 0.061 | 0.340 | 0.032 | 0.169 | 0.169 |
Cefepime | 0.071 | 0.040 | 0.832 | 0.097 | 0.033 | 0.056 |
Gentamycin | 0.097 | 0.020 | 0.065 | 0.009 | 0.832 | 0.117 |
Ciprofloxacin | 0.193 | 0.080 | 0.073 | 0.043 | 0.193 | 0.146 |
Amikacin | 0.169 | 0.061 | 0.340 | 0.032 | 0.169 | 0.088 |
Norfloxacin | 0.071 | 0.040 | 0.832 | 0.097 | 0.033 | 0.077 |
Aztreonam | 0.097 | 0.020 | 0.065 | 0.009 | 0.832 | 0.089 |
Tobramycin | 0.193 | 0.080 | 0.073 | 0.043 | 0.193 | 0.193 |
Piperacillin | 0.169 | 0.061 | 0.340 | 0.032 | 0.169 | 0.169 |
Piperacillin/tazobactam | 0.071 | 0.040 | 0.832 | 0.097 | 0.033 | 0.056 |
MDR | 0.218 | 0.824 | 0.343 | 0.383 | 0.647 | 0.052 |
β-lactamase-producer strain | ||||||
class A β-lactamases (ESBL) | 0.077 | 0.252 | 0.005 | 0.050 | 0.027 | 0.079 |
class B β-lactamases (MBL) | 0.089 | 0.085 | 0.063 | 0.006 | 0.045 | 0.035 |
class A β-lactamases (KPC) | 0.193 | 0.080 | 0.073 | 0.043 | 0.025 | 0.044 |