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. 2020 Jun 30;13:6303–6314. doi: 10.2147/OTT.S250412

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© 2020 Nie et al.

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GRHL2 expression activated ERK/MAPK signaling pathways in vitro. (A, B) Western blot was used to detect the expression of Fas, caspase3, Ki-67, Cyclin D1, p-ERK and total ERK proteins in SKOV3/DDP-shGRHL2 or SKOV3/DDP-shcontrol cells, respectively. *P< 0.05 vs SKOV3/DDP-shcontrol. (C, D) Western blot was used to evaluate the expression of Fas, caspase3, Ki-67, Cyclin D1, p-ERK and total ERK proteins in SKOV3-GRHL2, SKOV3-control cells and SKOV3-GRHL2 cells treated with U0126 (10.0 μM), respectively. *P<0.05 vs SKOV3-control; ΔP<0.05 vs SKOV3-GRHL2.

Note: Data were expressed as mean±SD.