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GRHL2 expression increased cisplatin-resistance in vivo. (A, B) The growth in mice of tumors developed from SKOV3/DDP-shGRHL2 or SKOV3/DDP-shcontrol cells were treated with cisplatin (3.0 mg/kg six times with a gap of 3 days). **;P< 0.01 vs SKOV3/DDP -shcontrol. (C, D) The growth in mice of tumors developed from SKOV3-GRHL2 or SKOV3-control cells were treated with cisplatin (3.0 mg/kg six times with a gap of 3 days). **P< 0.01 vs SKOV3-control cells.
Note: n=3 per group.
