Table 3.
Univariate and Multivariate Analysis for the Association Between Clinical Characteristics and Overall Survival in Patients with SOC
| Variable | Univariate | P value | Multivariate | P value |
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | |||
| Age(year) | ||||
| <50 | 1 | 1 | ||
| ≥50 | 1.953 (1.189–3.209) | 0.008 | 1.966 (1.117–3.460) | 0.019 |
| FIGO stage | ||||
| I–II | 1 | 1 | ||
| III–IV | 6.691 (3.155–14.192) | <0.001 | 5.297 (2.256–12.437) | <0.001 |
| Histological grade | ||||
| Low | 1 | 1 | ||
| High | 1.922 (1.091–3.389) | 0.024 | 0.904 (0.456–1.794) | 0.773 |
| Lymph node invasion | ||||
| Negative | 1 | 1 | ||
| Positive | 3.576 (1.994–6.412) | <0.001 | 0.647 (0.238–1.762) | 0.395 |
| Tumor residual(cm) | ||||
| Optimal(≤1) | 1 | 1 | ||
| Sub-optimal(>1) | 3.967 (2.213–7.113) | <0.001 | 2.092 (0.802–5.458) | 0.131 |
| GRHL2 expression | ||||
| Low | 1 | 1 | ||
| High | 5.717 (3.202–10.207) | <0.001 | 4.880 (2.559–9.308) | <0.001 |
Note: The bold number represents the P-values with significant differences (P<0.05).
Abbreviations: HR, hazard ratio; CI, confidence intervals.