Table 3.
Multivariable Cox Proportional Hazards model of freedom from post-heart transplant death or re-transplantation
| 95% Confidence Interval | ||||
|---|---|---|---|---|
| Predictor | Hazard Ratio | Lower | Upper | p-value |
| New allocation system | 1.18 | 0.90 | 1.55 | 0.228 |
| Donor age (per 5 years) | 1.09 | 1.05 | 1.12 | <0.001 |
| Recipient age (per 5 years) | 1.05 | 1.01 | 1.08 | 0.004 |
| Recipient male sex | 0.93 | 0.78 | 1.10 | 0.379 |
| Recipient ethnicity (reference: White) | ||||
| Black | 1.03 | 0.85 | 1.24 | 0.766 |
| Hispanic | 1.18 | 0.92 | 1.52 | 0.181 |
| Other | 0.91 | 0.64 | 1.30 | 0.616 |
| Donor/recipient sex mismatch | 1.09 | 0.88 | 1.34 | 0.432 |
| Recipient heart failure etiology (reference: ischemic) | ||||
| Non-ischemic dilated | 0.92 | 0.69 | 0.98 | 0.026 |
| Other | 0.92 | 0.74 | 1.16 | 0.494 |
| Recipient durable LVAD support | 1.12 | 0.95 | 1.34 | 0.186 |
| Recipient ECMO support | 2.97 | 2.06 | 4.28 | <0.001 |
| Recipient temporary VAD support | 1.10 | 0.71 | 1.73 | 0.667 |
| Recipient IABP support | 1.07 | 0.83 | 1.38 | 0.616 |
| Recipient prior cardiac surgery | 1.29 | 1.10 | 1.51 | 0.002 |
| Graft ischemic time (per hour) | 1.20 | 1.12 | 1.28 | <0.001 |
| Transplant center annualized volume | ||||
| <25 (per 5 transplants) | 0.87 | 0.82 | 0.93 | <0.001 |
| >25 (per 5 transplants) | 1.19 | 1.09 | 1.30 | <0.001 |
LVAD, left ventricular assist device; ECMO, extracorporeal membrane oxygenation; VAD, ventricular assist device; IABP, intraaortic balloon pump