Figure 2.

Stereoviews of Polder omit maps of 3a in complex with HDAC10 (contoured at 6.0 σ, PDB 6VNQ). Atoms are color‐coded as follows: C=light gray (HDAC10), orange (major conformer of 3a), or maroon (minor conformer of 3a), N=blue, O=red, Zn²⁺=gray sphere, and solvent=small red spheres. Metal coordination interactions are shown as solid black lines, and hydrogen bonds are shown as dashed black lines. A) Both conformers in complex with HDAC10. B) Major conformer in complex with HDAC10. C) Minor conformer in complex with HDAC10.