Table 1.
The main information of enrolled studies in the meta-analysis.
| Study | Year | Country | Tumor types | Sample size | Sample | Detection method | Cutoff value | Follow-up (year) | Outcome measures | Analysis type | NOS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Chen | 2019 | China | Osteosarcoma | 127 | Tissues | qRT-PCR | ROC curve | 16 years | OS CP | Multivariate | 9 |
| Fei | 2018 | China | Glioma | 60 | Tissues | qRT-PCR | Mean | 5 years | OS CP | Univariate | 8 |
| Hong | 2018 | China | Ovarian cancer | 76 | Tissues | qRT-PCR | Median | 6 years | OS CP | Multivariate | 9 |
| Ma | 2020 | China | Breast cancer | 60 | Tissues | qRT-PCR | Mean | NA | CP | NA | 7 |
| Peng | 2020 | China | Acute myeloid leukemia | 62 | Bone marrow | qRT-PCR | Median | 5 years | OS CP | Univariate | 8 |
| Shi | 2020 | China | Non-small cell lung cancer | 32 | Tissues | qRT-PCR | Median | 5 years | OS CP | Univariate | 9 |
| Sui | 2020 | China | Papillary thyroid carcinoma | 42 | Tissues | qRT-PCR | Mean | NA | CP | NA | 8 |
| Tian | 2019 | China | Intrahepatic cholangiocarcinoma | 52 | Tissues | qRT-PCR | NA | 5 years | OS CP | Multivariate | 8 |
| Xuan | 2019 | China | Gastric cancer | 60 | Tissues | qRT-PCR | Median | 6 years | OS MFS | Univariate | 8 |
| Zahra | 2019 | Iran | Breast cancer | 80 | Tissues | qRT-PCR | NA | NA | CP | NA | 7 |
| Zhang | 2016 | China | Hepatocellular carcinoma | 144 | Tissues | qRT-PCR | NA | 5 years | OS RFS DFS CP | Multivariate | 8 |
| Zhang | 2018 | China | Hepatocellular carcinoma | 70 | Tissues | qRT-PCR | NA | 2 years | OS CP | Univariate | 8 |
| Zheng | 2019 | China | Osteosarcoma | 54 | Tissues | qRT-PCR | Median | 10 years | OS | Univariate | 9 |