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. 2020 Jul 4;19:160. doi: 10.1186/s12944-020-01336-1

Table 1.

Characteristics of the study participants according to gender

Variables Men (n = 441) Women (n = 217) P Value
Age, year 64.6 ± 11.2 68.5 ± 10.7 < 0.001
Systolic blood pressure, mmHg 152.8 ± 23.8 154.1 ± 26.0 0.522
Diastolic blood pressure, mmHg 88.7 ± 16.0 84.7 ± 14.6 0.002
Hypertension, n (%) 311 (70.5) 165 (76.0) 0.137
Diabetes mellitus, n (%) 144 (32.7) 74 (34.1) 0.711
Current smoking, n (%) 251 (56.9) 4 (1.8) < 0.001
Previous stroke, n (%) 131 (29.7) 56 (25.8) 0.297
Coronary heart disease, n (%) 51 (11.6) 29 (13.4) 0.507
Number of ICAS lesions 0 (0–1) 0 (0–1) 0.771
NCAS 238 (54.0) 128 (59.0) 0.223
Isolated ICAS 115 (26.1) 67 (30.9) 0.196
Isolated ECAS 38 (8.6) 8 (3.7) 0.020
ICAS and ECAS 50 (11.3) 14 (6.5) 0.047
TC, mmol/L 4.35 ± 1.06 4.67 ± 1.10 < 0.001
TG, mmol/L 1.66 ± 1.23 1.62 ± 1.01 0.664
HDL-C, mmol/L 1.09 (0.94–1.24) 1.26 (1.09–1.51) < 0.001
LDL-C, mmol/L 2.82 ± 0.91 2.97 ± 0.99 0.061
Non-HDL-C, mmol/L 3.16 (2.48–3.90) 3.21 (2.53–3.96) 0.384
RC, mmol/L 0.42 ± 0.40 0.37 ± 0.35 0.121
Apo A-I, g/L 1.22 ± 0.35 1.40 ± 0.27 < 0.001
Apo B, g/L 0.99 ± 0.53 0.96 ± 0.29 0.520
Lipid Ratio
 TC/HDL-C 4.12 ± 1.37 3.74 ± 1.22 0.001
 TG/HDL-C 1.71 ± 1.77 1.45 ± 1.67 0.069
 LDL-C/HDL-C 2.68 ± 1.06 2.39 ± 0.94 0.001
 RC/HDL-C 0.44 ± 0.53 0.35 ± 0.55 0.036
 Non- HDL-C/HDL-C 3.12 ± 1.37 2.73 ± 1.22 0.001
 Apo B/HDL-C 2.25 (1.65–2.91) 1.87 (1.44–2.48) < 0.001
 Apo B/apo A-I 0.78 (0.60–0.98) 0.69 (0.53–0.86) < 0.001

ICAS intracranial atherosclerotic stenosis, ECAS extracranial atherosclerotic stenosis, NCAS no cerebral atherosclerotic stenosis, TC total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, RC remnant cholesterol, Non-HDL-C non-high-density lipoprotein cholesterol, Apo B apolipoprotein B, Apo A-I apolipoprotein A-I

Results are expressed as mean ± standard deviation, median with interquartile range or n (%)