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. 2020 Jul 4;19:160. doi: 10.1186/s12944-020-01336-1

Table 2.

Comparison of AUC for each evaluated variable in predicting ICAS

Total Men Women
AUC(95% CI) AUC(95%CI) AUC(95%CI)
Lipid measures
 TC 0.543 (0.498–0.589) 0.537 (0.481–0.592) 0.562 (0.482–0.642)
 TG 0.525 (0.480–0.570) 0.499 (0.444–0.554) 0.576 (0.500–0.652)
 HDL-C 0.462 (0.417–0.507) 0.480 (0.426–0.535) 0.435 (0.356–0.514)
 LDL-C 0.555 (0.510–0.601) 0.547 (0.491–0.603) 0.573 (0.493–0.653)
 Non-HDL-C 0.559 (0.513–0.604) 0.543 (0.488–0.599) 0.590 (0.511–0.669)
 RC 0.538 (0.493–0.583) 0.529 (0.475–0.584) 0.558 (0.481–0.635)
 Apo A-I 0.456 (0.411–0.501) 0.465 (0.410–0.520) 0.424 (0.345–0.504)
 Apo B 0.576 (0.531–0.622) 0.561 (0.505–0.617) 0.605 (0.527–0.683)
Lipid ratios
 TC/HDL-C 0.566 (0.521–0.611) 0.546 (0.491–0.601) * 0.608 (0.531–0.684)
 TG/HDL-C 0.535 (0.490–0.579) * 0.511 (0.456–0.566) * 0.580 (0.503–0.657)
 LDL-C/HDL-C 0.570 (0.525–0.615) 0.555 (0.499–0.611) 0.603 (0.526–0.680)
 RC/HDL-C 0.544 (0.500–0.589) 0.530 (0.475–0.584) 0.575 (0.498–0.652)
 Non- HDL-C/HDL-C 0.566 (0.521–0.611) 0.546 (0.491–0.601) * 0.608 (0.531–0.684)
 Apo B/ HDL-C 0.578 (0.533–0.623) 0.562 (0.506–0.617) 0.617 (0.541–0.693)
 Apo B/apo A-I 0.588 (0.543–0.633) 0.579 (0.523–0.634) 0.613 (0.536–0.690)

TC total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, RC remnant cholesterol, Non-HDL-C non-high-density lipoprotein cholesterol, Apo B apolipoprotein B, Apo A-I apolipoprotein A-I, AUC area under the curve; 95%CI 95% confidence interval, ICAS intracranial atherosclerotic stenosis. * P < 0.05, AUC were compared with apo B/apo A-I ratio in lipid ratios