Table 2.
Recommendations of herbal prescription for prevention and treatment for COVID-19 patients by consensus.
| Recommendations of herbal prescription for COVID-19 patientsa | Herbal preparation |
|---|---|
| Prevention | |
| Respiratory health of adults in the COVID-19 epidemic. | Youngyopaedoc-san + Bojungikgitang (Lianqiao baidu san + Buzhong Yiqi Tang) or Youngyopaedoc-san + Saengmaek-san (Lianqiao baidu san + Shengmai Yin) |
| – Clinical consideration: For high-risk adults with the possibility of close contact with a patient, Youngyopaedoc-san + Bojungikgitang is suitable for qi deficiency and Youngyopaedoc-san + Saengmaek-san for fluid–humor deficiency as preventive interventions. | |
| Treatment Herbal preparations for people who contacted patient(s) with COVID-19 | |
| Asymptomatic adults who came in close contact with patient(s) with COVID-19 | Youngyopaedoc-san + Bulhwangeumjeonggi-san (Lianqiao baidu san + Buhuanjin Zhengqi San) or Youngyopaedoc-san + Bojungikgi-tang (Lianqiao baidu san + Buzhong Yiqi Tang) |
| – Clinical consideration: Consider Youngyopaedoc-san + Bulhwangeumjeonggi-san (Lianqiao baidu san + Buhuan Zhengqi San) for asymptomatic, self-isolated adults who came in close contact with patients with COVID-19 and alternatively Youngyopaedoc-san + Bojungikgi-tang (Lianqiao baidu san + Buzhong Yiqi Tang) for the high-risk group (the old and infirm). | |
| Mild symptomatic patients with COVID-19 and wind-warmth disease invading the lungs. | Youngyopaedoc-san + Galgunhaegui-tang (Lianqiao baidu san + Gegen Jieji Tang) |
| – Clinical consideration: Only if there are symptoms of external contraction and respiratory dysfunction due to wind-warmth disease, such as chills with fever, mild chills, weakness, heaviness of head and body, muscle pain, dry cough with thick sputum, sore throat, dry mouth with anorexia, excess thirst, anhidrosis or hypohidrosis. | |
| Mild symptomatic patients with COVID-19 and cold-dampness disease depressing the lungs. | Galgunhaegui-tang + Bulhwangeumjeonggi-san (Gegen Jieji Tang + Buhuanjin Zhengqi San) |
| – Clinical consideration: Only if there are symptoms of external contraction due to cold and dampness, respiratory symptoms, including fever, weakness, body aches, cough, sputum, chest tightness, and choke, digestive symptoms, including anorexia, nausea, vomiting and sticky stool with discomfort. | |
| Mild symptomatic patients with COVID-19 and dampness-heat disease in the lungs. | Sosiho-tang + Bulhwangeumjeonggi-san (Xiao Chaihu Tang + Buhuanjin Zhengqi San) |
| – Clinical consideration: Only if there are symptoms of external contraction due to heat and dampness, respiratory symptoms, including mild or no fever, mild chills, weakness, heaviness of head and body, muscle ache, dry cough with thick sputum, sore throat, dry mouth with anorexia, excess thirst, anhidrosis or hypohidrosis, digestive symptoms, including oppression in the chest and gastric stuffiness or nausea with anorexia and loose stool or sticky stool with discomfort. | |
| Recovery stage | |
| Patients with COVID-19 in the recovery stage. | Samchulkunbi-tang + Saengmaek-san (Shen Zhu Jianpi Tang + Shengmai Yin) or Samchulkunbi-tang + Chungseuiki-tang (Shen Zhu Jianpi Tang + Qingshu Yiqi Tang) |
| – Clinical consideration: Recovery means two consecutive sets of negative test results, performed more than 24 h apart. | |
| Chungpaebaedoc-tang (Qingfeipaidu-Tang) and its replacement medicines: | |
| Consider the use of for symptom improvement in adults with COVID-19. | Chungpaebaedoc-tang (Qingfeipaidu-Tang) |
| – Clinical consideration: Consider the severity of symptoms of external contraction and respiratory dysfunctions induced by heat as well as digestive symptoms due to dampness: Symptom comparison between Korean patients and Chinese patients is required. ◦ If there are no digestive symptoms due to dampness, caution for adverse reactions due to dryness is required. ◦ If heat sense becomes severe, focus on the herbal composition of Mahaenggamseok-tang (Ma Xing Gan Shi Tang) and Sosiho-tang (Xiao Chaihu Tang); To resolve cough, focus on the herbal composition of Saganmahwang-tang (Shegan ma huangtang); If digestive symptoms are present, including stool problems, focus on the herbal composition of Oryeong-san (Wu lin San) and Gwakhyangjeonggi-san (Huoxiang Zhengqi San). | |
| Adults with COVID-19 (replacement medicine of Chungpaebaedoc-tang (Qingfeipaidu-tang)) | Galgunhaegui-tang (Gegen Jieji Tang), Sosiho-tang (Xiao Chaihu Tang), and Bulhwangeumjeonggi-san (Buhuanjin Zhengqi San) |
COVID-19, coronavirus disease 2019.
a
Recommendation level is good practice point.