Table 1.
Study Design of the Included Studies
| Study | Year | No. of Patients (CA/IVUS) | Design | Stent Type | Follow‐Up, mo |
|---|---|---|---|---|---|
| AIR‐CTO13 | 2015 | 115/115 | RCT | DES | 12 |
| AVID14 | 2009 | 406/394 | RCT | BMS | 12 |
| Chen et al15 | 2012 | 123/123 | Observational, PSM | DES | 12 |
| Choi et al16 | 2019 | 4331/1674 | Observational | DES | 64 |
| CTO‐IVUS17 | 2015 | 201/201 | RCT | DES | 12 |
| de la Torre Hernandez18 | 2014 | 505/505 | Observational, PSM | DES | 36 |
| DIPOL19 | 2007 | 80/83 | RCT | BMS | 6 |
| EXELLENT20 | 2013 | 463/463 | Observational, PSM | DES | 12 |
| Gao et al21 | 2014 | 291/291 | Observational, PSM | DES | 12 |
| HOME DES IVUS22 | 2010 | 105/105 | RCT | DES | 18 |
| Hong et al23 | 2014 | 201/201 | Observational, PSM | DES | 24 |
| IVUS‐XPL24 | 2015 | 700/700 | RCT | DES | 12 |
| Kim et al (RESET)25 | 2013 | 274/269 | RCT | DES | 12 |
| MATRIX26 | 2011 | 548/548 | Observational, PSM | DES | 24 |
| OPTICUS27 | 2001 | 275/273 | RCT | BMS | 12 |
| Roy et al28 | 2008 | 884/884 | Observational, PSM | DES | 12 |
| ULTIMATE29 | 2018 | 724/724 | RCT | DES | 12 |
| Wakabayashi et al30 | 2012 | 637/637 | Observational, PSM | BMS/DES | 12 |
| Witzenbichler et al31 | 2014 | 5234/3349 | Observational | DES | 12 |
AIR‐CTO indicates Angiographic and Clinical Comparisons of Intravascular Ultrasound‐Versus Angiography‐Guided Drug‐Eluting Stent Implantation for Patients With Chronic Total Occlusion Lesions; AVID, Angiography Versus Intravascular Ultrasound‐Directed Stent Placement; BMS, bare metal stent; CA, coronary angiography; CTO‐IVUS, Intravascular Ultrasound‐Guided Chronic Total Occlusion Intervention; DES, drug‐eluting stent; DIPOL, Direct Stenting vs Optimal Angioplasty Trial; EXCELLENT, Efficacy of Xience/Promus Versus Cypher in Reducing Late Loss After Stenting; HOME DES IVUS, Long‐Term Health Outcome and Mortality Evaluation After Invasive Coronary Treatment Using Drug Eluting Stents With or Without the IVUS Guidance; IVUS, intravascular ultrasound; IVUS‐XPL, Intravascular Ultrasound Guidance on Outcomes of Xience Prime Stents in Long Lesions; REST, Real Safety and Efficacy of a 3‐Month Dual Antiplatelet Therapy Following Zotarolimus‐Eluting Stents Implantation; MATRIX, Comprehensive Assessment of Sirolimus‐Eluting Stents in Complex Lesions; OPTICUS, Optimization With ICUS to Reduce Stent Restenosis; PSM, propensity score matching; RCT, randomized controlled trial; ULTIMATE, Intravascular Ultrasound Guided Drug Eluting Stents Implantation in “AllComers” Coronary Lesions trial.