Table 2.

Hemodynamics, Ventricular Function, and FT‐CMR at Normoxia and Hyperoxia

	Controls			Patients With CAD
	Room Air	O2	P Value	Room Air	O2	P Value
Hemodynamics
Heart rate, bpm	66±10	64±13	0.472	62±12	61±10	0.332
Systolic BP, mm Hg	107±10	111±15	0.230	130±16	132±17	0.312
Diastolic BP, mm Hg	54±6	60±7	0.002*	75±8	76±9	0.594
SpO2, %	96.6±1.2	99.4±0.7	<0.001*	96.3±1.3	99.2±0.8	<0.001*
LV function
Ejection fraction, %	68.4±7.1	69.3±4.9	0.161	60.0±11.6	58.3±11.8	0.127
End‐diastolic volume index, mL/m2	85±16	90±18	0.952	75±15	76±14	0.452
End‐systolic volume index, mL/m2	26±5	27±6	0.360	30±12	31±12	0.186
Stroke volume index, mL/m2	58±15	62±14	0.609	44±10	44±11	0.857
Cardiac index, L/min/m2	4.06±1.10	3.87±1.23	0.051	2.89±0.84	2.75±0.79	0.040*
Mass index, g/m2	63±15			68±11
FT‐CMR
Circumferential
Peak strain, %	−22.0±2.0	−21.0±1.7	0.149	−19.7±4.1	−19.4±4.1	0.219
Time to peak strain, ms	291±25	311±35	0.010*	328±51	346±64	0.017*
Systolic strain rate, /s	−1.25±0.38	−1.17±0.24	0.608	−0.99±0.29	−0.96±0.25	0.152
Diastolic strain rate, /s	1.78±0.31	1.63±0.38	0.316	0.94±0.44	0.80±0.32	0.048*
Radial
Peak strain, %	42.6±6.3	39.3±6.0	0.090	37.1±11.3	36.4±11.2	0.411
Time to peak strain, ms	294±26	318±30	0.010*	326±49	339±56	0.193
Systolic strain rate, /s	2.47±0.61	2.11±0.58	0.005*	1.95±0.81	1.80±0.62	0.072
Diastolic strain rate, /s	−3.22±0.64	−2.83±0.52	0.055	−1.89±0.92	−1.71±0.66	0.158
Displacement, mm	7.02±0.93	6.58±0.84	0.032*	6.55±1.47	6.51±1.40	0.589
Time to displacement, ms	294±26	312±48	0.176	333±54	344±71	<0.001*
Systolic velocity, mm/s	38.37±8.73	35.66±9.23	0.011*	32.29±9.48	31.31±7.90	0.304
Diastolic velocity, mm/s	−55.48±14.23	−49.42±8.87	0.125	−33.40±17.40	−30.68±16.10	0.089

Global measurements are displayed as mean±SD. BP indicates blood pressure; bpm, beats per minute; CAD, coronary artery disease; FT‐CMR indicates feature tracking cardiovascular magnetic resonance; LV, left ventricular; SpO₂, peripheral oxygen saturation. *P<0.05 indicates a significant change from normoxemia (room air) to hyperoxia.