Table 1.

Characteristics of Participating Studies

Study	Study Design	Original Population	Available Data	Outcome Data Collection	Website
BWHHS16	Cohort	4286 women aged 60–79 y recruited from general practices in 23 towns across the United Kingdom	Baseline: 2000 Follow‐up: 12 yb	Biennial medical record review (with validation checks) Death certificates obtained from the National Health Service (NHS) Central Registration	http://www.ucl.ac.uk/british-womens-heart-health-study
BRHS17	Cohort	7735 men aged 40–59 y recruited from general practices in 24 towns across the United Kingdom	Baseline: 1998–2000 Follow‐up: 10 yb	Biennial medical record review (with validation checks) Death certificates obtained from the NHS Central Registration	http://www.ucl.ac.uk/pcph/research-groups-themes/brhs-pub
WHII18	Cohort	10 308 civil servants recruited from the United Kingdom	Baseline: 1997–1999 Follow‐up: 12 yb	Self‐reported nonfatal events (at all phases) supplemented by information on coronary events identified by research clinic ECGs, and through verification of primary care and hospital records	http://www.ucl.ac.uk/whitehallII
SABRE19	Cohort	4857 individuals from European, Indian Asian and African Caribbean ancestry aged 40–69 y recruited from workplaces and general practices in the United Kingdom	Baseline: 1988–1990 Follow‐up: 25 yb	Identified from primary‐care and hospital records and from participant questionnaire responses Death certificates obtained from the NHS Central Registration	http://www.sabrestudy.org/
CaPS20	Cohort	2512 men aged 45–59 y from the town of Caerphilly and adjoining villages	Baseline: 1989–1993 Follow‐up: 12 yb	Self‐reported nonfatal events were validated from medical records and fatal events were collected from death certificates	http://www.bris.ac.uk/social-community-medicine/projects/caerphilly/about/
UKCTOCS21	Nested case‐control	1617 CHD and 863 stroke‐matched female cases selected for a case‐control study nested in a randomized controlled trial of ovarian cancer screeninga	Baseline: 2001–2005 Follow‐up: 10 yb	Nonfatal and fatal events collected from medical records and death certificates, respectively	http://www.instituteforwomenshealth.ucl.ac.uk/womens-cancer/gcrc/ukctocs

BRHS indicates British Regional Heart Study; BWHHS, British Women's Heart and Health Study; CaPS, Caerphilly Prospective Study; CHD, coronary heart disease; SABRE, Southall and Brent Revisited cohort; UKCTOCS, United Kingdom Collaborative Trial of Ovarian Cancer Screening; WHII, Whitehall‐II Study.

^aMaximum follow‐up length in years.

^bCases were matched with controls (known not to have experienced cardiovascular events before 2010) by age, recruitment center, and time of blood sampling.