Table 3. Function of genes upregulated in dNK and TiNK cells.
Gene | Description | Function | Ref. |
---|---|---|---|
VEGFA | Growth Factor | Physiological/pathological angiogenesis; vascular permeability; tumorigenesis | [62] |
VEGFB | Growth Factor | Physiological/pathological angiogenesis; maintenance of blood vessels | [63] |
ANG2 | Growth Factor | Physiological/pathological angiogenesis; vascular permeability; tumorigenesis | [64] |
IL6 | Cytokine | Acute and chronic inflammation; leukocyte recruitment | [65] |
IL8 | Cytokine | Acute and chronic inflammation; neutrophil recruitment | [66] |
CCL3 | Chemokine | Acute inflammation; leukocyte recruitment | [67] |
CXCL1 | Chemokine | Angiogenesis, inflammation, wound healing | [68] |
CCR7 | Receptor | Homing to lymphoid organs; recognizes CCL19 and CCL21 ligands | [69] |
CD146 | Receptor | NK cell adhesion; angiogenesis; immune response | [70] |