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. 2020 Jun 30;11(26):2571–2585. doi: 10.18632/oncotarget.27654

Table 3. Function of genes upregulated in dNK and TiNK cells.

Gene Description Function Ref.
VEGFA Growth Factor Physiological/pathological angiogenesis; vascular permeability; tumorigenesis [62]
VEGFB Growth Factor Physiological/pathological angiogenesis; maintenance of blood vessels [63]
ANG2 Growth Factor Physiological/pathological angiogenesis; vascular permeability; tumorigenesis [64]
IL6 Cytokine Acute and chronic inflammation; leukocyte recruitment [65]
IL8 Cytokine Acute and chronic inflammation; neutrophil recruitment [66]
CCL3 Chemokine Acute inflammation; leukocyte recruitment [67]
CXCL1 Chemokine Angiogenesis, inflammation, wound healing [68]
CCR7 Receptor Homing to lymphoid organs; recognizes CCL19 and CCL21 ligands [69]
CD146 Receptor NK cell adhesion; angiogenesis; immune response [70]