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. 2020 Jun 30;11(26):2464–2483. doi: 10.18632/oncotarget.27614

Figure 9. miR-708 and the arachidonic acid pathway.

Figure 9

Illustration of miR-708’s relationship to the AA signaling pathway. Blue lettering indicates short-lived intermediates and mature signaling molecules within the AA pathway. Red lettering illustrates a negative correlation between miR-708 and AA-related gene’s mRNA expression in LUSC patients. Green lettering illustrates a positive correlation between miR-708 and AA-related gene’s mRNA expression in LUSC patient. Black lettering illustrates no significant correlation. Solid black lines indicate metabolic steps, while dotted black lines indicate eicosanoid signaling to respective receptors. (**) Represents predicted miR-708 targets from microRNA. org and miRTarBase.