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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Laryngoscope. 2020 Jan 6;130(12):E773–E781. doi: 10.1002/lary.28493

TABLE I.

Patient Characteristics.

Enrollment Biopsies for Glutaminase Expression, n = 6 Biopsies for Cell Culture, n = 6
Median age, yr (range) 50 (27–72) 43.2 (25–72)
Sex, male/female, n (%)   0 (0)/6 (100)   4 (67)/2 (33)
Tobacco use, n (%)
 Current   0 (0)   0 (0)
 Former   2 (33)   2 (33)
 Never   4 (67)   4 (67)
Cotton-Meyer grade, n (%)
 1   1 (17)   2 (33)
 2   2 (33)   1 (17)
 3   3 (50)   2 (33)
 4   0 (0)   1 (17)
Tracheotomy, n (%)
 Presented with   2 (33)   4 (67)
 Required during biopsy   0 (0)   0 (0)
Etiology, n (%)
 Iatrogenic   6 (100)   6 (100)
 Congenita   0 (0)   0 (0)
Medication utilization, n (%)
 Autoimmune/autosuppressant therapy   0 (0)   0 (0)
 Oxygen therapy   0 (0)   0 (0)
 Inhaled steroid   1 (17)   1 (17)
 PPI   2 (33)   1 (17)
Comorbidities, n (%)
 Asthma   0 (0)   0 (0)
 Chronic obstructive   0 (0)   0 (0)
 Depression   3 (50)   2 (33)
 Laryngopharyngeal reflux   0 (0)   0 (0)
 Hemiplegia   0 (0)   1 (17)
 Hypertension   2 (33)   3 (50)
 Obstructive sleep apnea   0 (0)   1 (17)
 Solid tumor   0 (0)   0 (0)
 Inflammatory tissue disease   0 (0)   0 (0)
 Aspiration pneumonia secondary to dysphagia   0 (0)   0 (0)
 Months from injury to treatment, mean ± SD  14.6 ± 8.13 13.8 ± 9.23

PPI = proton pump inhibitor; SD = standard deviation.