TABLE I.
Enrollment | Biopsies for Glutaminase Expression, n = 6 | Biopsies for Cell Culture, n = 6 |
---|---|---|
Median age, yr (range) | 50 (27–72) | 43.2 (25–72) |
Sex, male/female, n (%) | 0 (0)/6 (100) | 4 (67)/2 (33) |
Tobacco use, n (%) | ||
Current | 0 (0) | 0 (0) |
Former | 2 (33) | 2 (33) |
Never | 4 (67) | 4 (67) |
Cotton-Meyer grade, n (%) | ||
1 | 1 (17) | 2 (33) |
2 | 2 (33) | 1 (17) |
3 | 3 (50) | 2 (33) |
4 | 0 (0) | 1 (17) |
Tracheotomy, n (%) | ||
Presented with | 2 (33) | 4 (67) |
Required during biopsy | 0 (0) | 0 (0) |
Etiology, n (%) | ||
Iatrogenic | 6 (100) | 6 (100) |
Congenita | 0 (0) | 0 (0) |
Medication utilization, n (%) | ||
Autoimmune/autosuppressant therapy | 0 (0) | 0 (0) |
Oxygen therapy | 0 (0) | 0 (0) |
Inhaled steroid | 1 (17) | 1 (17) |
PPI | 2 (33) | 1 (17) |
Comorbidities, n (%) | ||
Asthma | 0 (0) | 0 (0) |
Chronic obstructive | 0 (0) | 0 (0) |
Depression | 3 (50) | 2 (33) |
Laryngopharyngeal reflux | 0 (0) | 0 (0) |
Hemiplegia | 0 (0) | 1 (17) |
Hypertension | 2 (33) | 3 (50) |
Obstructive sleep apnea | 0 (0) | 1 (17) |
Solid tumor | 0 (0) | 0 (0) |
Inflammatory tissue disease | 0 (0) | 0 (0) |
Aspiration pneumonia secondary to dysphagia | 0 (0) | 0 (0) |
Months from injury to treatment, mean ± SD | 14.6 ± 8.13 | 13.8 ± 9.23 |
PPI = proton pump inhibitor; SD = standard deviation.