Table 2.
Multivariate Analysis on Significant Predictors for HCC Recurrence.
| Parameter | Odd Ratio (95% CI) | P value |
|---|---|---|
| AFP pretransplant peak | 1.00 (1.00–1.00) | 0.62 |
| Poorly differentiated histology on explant (Yes/No) | 1.34 (0.85–2.12) | 0.21 |
| Microvascular invasion on explant (Yes/No) | 1.85 (1.17–2.93) | 0.008* |
| Macrovascular invasion on explant (Yes/No) | 1.54 (0.54–4.40) | 0.42 |
| Explant pathology within Milan criteria (Yes/No) | 0.55 (0.31–0.96) | 0.04* |
| Explant pathology within UCSF criteria (Yes/No) | 0.93 (0.52–1.66) | 0.8 |
| Number of lesions on explant | 1.17 (1.01–1.34) | 0.03* |
| Maximum size of tumor on explant | 1.06 (1.03–1.09) | 0.0004* |
| Sum of tumor size on explant | 0.97 (0.95–1.00) | 0.02* |
| Hepatocholangiocarcinoma (Yes/No) | 1.62 (0.80–3.28) | 0.18 |
| AFP post-transplant peak | 1.01 (1.01–1.02) | <0.0001* |
| Sirolimus exposure (Yes/No) | 0.37 (0.17–0.83) | 0.016* |
HCC, Hepatocellular carcinoma; CI, confidence interval; AFP, alpha-fetoprotein; UCSF, University of California San Francisco.
* P-value < 0.05.