Figure 5.

Characterization of iNSC Homing

Four patients were selected to assess the migration of iNSCs to distant, established GBM. U87-mCherry were implanted into the parenchyma of mice (n = 5), and iNSC-Cy5s were implanted ipsilaterally 1.5 mm away (A). Immunofluorescent analysis of postmortem tissue sections, 8 days postimplant, was used to stratify patients by tumor tropism (B). Blue arrows indicate day 1 iNSC injection site, and white arrows indicate iNSCs closest to tumor at day 7 postinjection.