. 2020 Apr 16;28(7):1706–1716. doi: 10.1016/j.ymthe.2020.04.007

Table 1.

Observed Seizure or Seizure-Associated Behaviors in Treated or Control-Injected Dnm1^Ftfl/Ftfl Mice

Postnatal Day	Group	Positive	Negative	Total	% Positive	p Value^a
14	control	25	19	44	56.8%	0.017
14	miDnm1a	8	21	29	27.6%	0.017
16	control	24	19	43	55.8%	0.156
16	miDnm1a	11	18	29	37.9%	0.156
18	control	39	3	42	92.9%	2 × 10⁻⁶
18	miDnm1a	12	17	29	41.4%	2 × 10⁻⁶
20	miDnm1a	5	19	24	20.8%	n.a.
22	miDnm1a	9	12	21	20.8%	n.a.
24	miDnm1a	7	13	20	35.0%	n.a.
26	miDnm1a	3	17	20	15.0%	n.a.
28	miDnm1a	1	19	20	5.0%	n.a.
30	miDnm1a	1	19	20	5.0%	n.a.

Fisher exact test, two-tail, 2 × 2 contingency analysis. Treated Dnm1^Ftfl/Ftfl mice show fewer seizures compared to control-injected Dnm1^Ftfl/Ftfl mice, and this is statistically significant at PND 14 and PND 18. At PND 18, four treated mice were removed from the study for histological analysis. n.a. - not applicable.