Table 2.
Heart rate and blood pressure of participants at baseline and each study day.
| Condition | Systole | Diastole | Heart rate | Systole | Diastole | Heart rate | Heart rate P-val. |
|---|---|---|---|---|---|---|---|
| BASELINE | |||||||
| Mean | 123.93 | 71.93 | 66.32 | ||||
| SD | 9.74 | 9.66 | 10.73 | ||||
| PREDOSE | POSTDOSE | ||||||
| PLACEBO | |||||||
| Mean | 121.39 | 70.82 | 67.86 | 116.25 | 69.75 | 62.14 | 0.11 |
| SD | 8.71 | 9.83 | 8.19 | 24.89 | 17.49 | 16.11 | |
| L-DOPA | |||||||
| Mean | 120.82 | 68.89 | 66.61 | 119.46 | 68.71 | 63.61 | 0.32 |
| SD | 9.66 | 7.92 | 10.62 | 9.12 | 9.34 | 9.80 | |
| HALOPERIDOL | |||||||
| Mean | 121.36 | 69.54 | 67.71 | 116.36 | 67.61 | 60.75 | <0.001 |
| SD | 9.78 | 7.95 | 10.03 | 9.68 | 7.77 | 10.09 | |
| P-val. | 0.21 | 0.36 | 0.72 | 0.012 | 0.07 | 0.2 | |
Formula for differences between sessions are “lmer (Systole/Diastole/HeartRate) ~ Drug Session + (1|ID)”. Paired t-tests were run for within-session heart rate.