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. 2020 Jun 30;13:2307–2316. doi: 10.2147/DMSO.S251491

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© 2020 Zhou et al.

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GW501516 decreased fasting blood glucose (FBG), fasting insulin (FINS), HOMA-islet resistance index (HOMA-IR) expression and increased insulin sensitivity index (ISI) expression in GDM rats. (A) Expression level of FBG in rats. (B) Expression level of FINS in rats. (C) Expression level of HOMA-IR. Calculation method: HOMA-IR = FBG ×FINS/22.5. (D) Expression level of ISI. Calculation method: ISI=1/(FBG×FINS), where insulin unit was converted as (1 ng/mL=21.2 mIU/L). n=10, ***p<0.001 vs control; #p<0.05, ##p<0.01, ###p<0.001 vs GDM.