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. 2020 Jun 30;12:5085–5098. doi: 10.2147/CMAR.S242135

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© 2020 Li et al.

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MiR-628-5p/MAGT1 axis functioned in Sev-mediated glioma progression. (A and B) The protein level of MAGT1 in glioma cells treated with Sev, Sev + anti-miR-628-5p or Sev + anti-miR-628-5p + si-MAGT1, as well as matched controls was detected by Western blot. (C and D) The cell viability was assessed by CCK8 assay. (E and F) Cell apoptosis was detected by flow cytometry. (G and H) Western blot was hired to check the protein levels of Bcl-2, Bax and cleaved caspase 3 in samples. (I–L) Transwell assay was done to estimate the capabilities of cell migration and invasion. (M–P) The rates of glucose uptake and lactate production were checked by corresponding colorimetric assay kit. (Q and R) Western blot was performed to measure the protein level of HK2 in samples. *P< 0.05. **P< 0.01. ***P< 0.001. ****P< 0.0001.