Figure 4.

Effects of miR-101 overexpression on cell viability, apoptosis and invasion of pancreatic cancer cells. (A, B) PANC-1 and SW1990 cells were transfected with mimics NC or miR mimics, and 24 h later, miR-101 expression in these transfected cells was determined by qRT-PCR. (C–J) PANC-1 and SW1990 cells were transfected with mimics NC or miR mimics, and 24 h later, cell viability was determined by MTT assay (C, D), cell apoptosis was evaluated with Caspase-3 Activity Assay Kit (E, F) and flow cytometry (G, H), and cell invasive ability was assessed with Transwell invasion assay (I, J). N = 3. *P<0.05 and **P<0.01.