. 2020 May 29;119(1):115–127. doi: 10.1016/j.bpj.2020.05.020

Table 2.

Performance Comparison with Commonly Used Protein Thermostability Prediction Methods

	FEP+	MM-GBSA	PoPMuSiC_sym	MUPRO	FoldX	Rosetta
MUE	0.85	NA	1.08	0.70	1.20	1.65
RMSE	1.11	NA	1.46	1.21	1.79	2.19
R²	0.68	0.39	0.27	0.36	0.22	0.39
Accuracy	0.85	0.74	0.65	0.77	0.70	0.64
Sensitivity	0.89	0.46	0.68	0.32	0.68	0.53
Specificity	0.84	0.86	0.64	0.94	0.70	0.68