Table 1.
Main characteristics stratified by quartiles of FGF-23 levels
| Parameter | All patients | Serum FGF-23 level (pg/ml) |
P | |||
|---|---|---|---|---|---|---|
| Quartile 1 70.0 (44.5–92.0) |
Quartile 2 189.0 (127.2–273.8) |
Quartile 3 638.5 (529.8–783.0) |
Quartile 4 3270 (1813.0–5115.5) |
|||
| Patients, n | 51 | 10 | 14 | 12 | 15 | |
| Age, yr | 48 (18–65) | 49 (21–59) | 47 (19–65) | 50 (20–63) | 48 (19–64) | 0.248 |
| Serum phosphate, mmol/l | 1.52 (1.29–1.87) | 1.30 (1.16–1.42) | 1.44 (1.22–1.58) | 1.54 (1.23–1.72) | 1.82 (1.54–2.10) | 0.020 |
| EF >50%, n (%) | 40 (78.4) | 10 (100) | 14 (100) | 8 (66.7) | 8 (53.33) | 0.025 |
| LV hypertrophy, n (%) | 35 (68.6) | 3 (30) | 6 (42.8) | 11 (91.7) | 15 (100) | 0.001 |
| E/A ratio | 1.3 (0.73–2.2) | 0.9 (0.76–1.45) | 1.1 (0.80–1.54) | 1.3 (0.87–2.1) | 1.6 (0.98–2.4) | 0.029 |
| LV diastolic dysfunction, n (%) | 33 (64.7) | 3 (28) | 6 (45) | 10 (83.3) | 14 (93.3) | 0.002 |
| Klotho, pg/ml | 410.5 (312.5–470.0) | 542.0 (515.0–603.5) | 454.0 (421.0–461.0) | 364.0 (330.0–399.0) | 267.0 (145.5–288.5) | 0.010 |
E/A ratio, transmitral early filling velocity/transmitral late filling velocity; EF, ejection fraction; FGF-23, fibroblast growth factor 23; LV, left ventricular.
Data are expressed as a median (interquartile range) or as frequency (percentage), as appropriate.