Table 1. Results of celecoxib solubility in different solvents and conductometric titration study to determine critical micelle concentration of sodium caseinate .
Solubility of celecoxib | |
Solvent | Solubility (µg/mL) |
Water | 6.10 ± 0.033 |
SIFSLS 1% | 240.52 ± 0.098 |
Phosphate buffer (pH 6.8) | 12.01 ± 0.026 |
Conductometric titration | |
Conc. (mg/mL) | Conductivity (K) (µS/cm) |
0.01 | 0.11 |
0.02 | 0.28 |
0.04 | 0.54 |
0.06 | 0.63 |
0.08 | 0.69 |
0.1 | 0.75 |
0.12 | 0.79 |
0.14 | 0.83 |
0.16 | 0.87 |
0.18 | 0.92 |
0.2 | 0.97 |
0.22 | 1.02 |