Table 2. Evaluation of casein nanocarriers .
Batch | Entrapment Efficiency (%) | Drug Loading (%) | Particle size (nm) | Zeta Potential (mV) | Polydispersity index | Cumulative release (%) (120 min) |
Casein nanoparticles (CNP) | ||||||
A1 (0.5%) | 72.08±1.2 | 25.02±0.28 | 259.06±1 | -23.6±0.1 | 0.436±0.001 | 78.57±0.7 |
A2 (1%) | 90.71±3.1 | 14.08±0.16 | 216.1±2 | -24.6±0.1 | 0.422±0.001 | 98.17±1.3 |
A3 (1.5%) | 82.26±2.3 | 10.02±0.14 | 222.53±4 | -24.5±0.1 | 0.371±0.002 | 92.84±1.4 |
re-assembled casein micelles (r-CM) | ||||||
B1 (0.5%) | 72.05±1.2 | 15.21±0.17 | 631.8±7 | -29.3±0.1 | 0.786±0.001 | 76.34±0.6 |
B2 (1%) | 90.65±3.4 | 9.44±0.12 | 665.3±6 | -28.9±0.5 | 0.587±0.001 | 89.24±1.5 |
B3 (1.5%) | 81.14±2.1 | 6.84±0.11 | 643.6±8 | -29.5±0.1 | 0.625±0.002 | 82.40±0.6 |
Casein nanocapsules (CNC) | ||||||
C1 (0.5%) | 72.03±1.4 | 8.54±0.12 | 394.6±5 | -32.3±0.1 | 0.197±0.002 | 11.85±0.9 |
C2 (1%) | 90.52±3.2 | 6.94±0.11 | 389.2±3 | -29.5±0.1 | 0.191±0.001 | 18.31±1.1 |
C3 (1.5%) | 80.15±2.4 | 5.85±0.10 | 396.4±4 | -30.5±0.1 | 0.262±0.001 | 13.50±0.6 |